Soft tissue cyst examples

Soft tissue sarcomas can develop in soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. They can be found in any part of the body. Most of them start in the arms or legs The type of cell that develops the genetic mutation determines what type of soft tissue sarcoma you have. For example, angiosarcoma begins in the lining of blood vessels, while liposarcoma arises from fat cells. Some types of soft tissue sarcoma include

An epidermoid cyst is a small, slow growing, benign cyst most commonly found on the face, head, neck, back, or genitals. It's usually caused by a buildup of keratin under the skin. It looks like a.. A cyst is a lesion that contains liquid or semisolid material. Examples of jaw tumors and cysts include: Ameloblastoma. This is a relatively common, slow-growing, usually noncancerous (benign) tumor. It develops most often in the jaw near the molars and can invade local structures such as bone and soft tissue Malignant soft tissue tumors are classified as sarcomas. These tumors are thought to arise from connective tissues other than bone, such as muscle, tendon, ligament, fat, and cartilage. They are rare. Only about 8,000 tumors of this type occur each year in the United States, representing only about 1% of all malignant tumors SPECIMENS: Cystic soft tissue mass, which will be sent to Pathology for pathologic diagnosis. CONDITION ON TRANSFER TO PAR: Good. INDICATIONS FOR PROCEDURE: The patient is a (XX)-year-old Hispanic female with an enlarging soft tissue mass to the posterolateral aspect of the right knee. She desires elective excision of the above There are 50 different types of soft tissue sarcomas, which can develop in many different locations and tissues within the body. Because of this great variability among soft tissue sarcomas, recommended treatment options will vary, depending upon the stage, grade, type and location of the tumor. Thus, developing an individualized treatment plan with your Cancer Treatment Centers of America.

What Is a Soft Tissue Sarcoma? - Cance

  1. Among the most common tumors which can be classified as benign soft tissue tumors are lipoma, angiolipoma, fibroma, benign fibrous histiocytoma, neurofibroma, schwannoma, neurilemmona, hemangioma, giant cell tumor of tendon sheath, and myxoma. Some conditions, like nodular fasciitis, are not tumors, but may require similar treatment
  2. Cysts and tumors are two common types of lumps. It can be hard to tell them apart because they're often found in the same places. For example, it's possible to have both ovarian cysts and ovarian..
  3. Kaposi's sarcoma is an example of an infection-induced soft tissue tumor -resulting from a type of herpes in patients who also have HIV. Most people with a soft tissue tumor do not have a well-defined cause for their tumor

cyst [sist] 1. bladder. 2. an abnormal closed epithelium-lined sac in the body that contains a liquid or semisolid substance. Most are harmless, but they should be removed when possible because they occasionally may change into malignant growths, become infected, or obstruct a gland. There are four main types of cysts: retention cysts, exudation cysts. Cysts occur commonly in numerous tissues and organs and are often named according to their particular anatomic location (for example ovarian cysts, bladder cysts, breast cysts, liver cysts, kidney cysts, pancreatic cysts, vaginal cysts, skin cysts, thyroid cysts). Certain types of cysts also have special designations and nomenclature

A cyst is an abnormal sac or pocket in bone or soft tissues which may contain fluid. There are many different kinds of cysts. The most important reason for removing a cyst is that over time they increase in size and may become harmful. Very large cysts may weaken the lower jaw bone to the point where it can break more easily Lipoma is the most common soft-tissue tumor that will be encountered by an orthopaedic surgeon and is one of the few soft-tissue masses that can be definitively identified on imaging. On MRI, the mass simply needs to be compared to the subcutaneous fat A lump or mass is the most common soft tissue sarcoma sign. The lump will form in the area in which the tumor is growing, and it may be accompanied by some pain if it is pressing on a nerve or muscle. Even if the lump isn't painful, if it continues to grow, or if it is located deep within an extremity or body cavity, consult your doctor Spectrum of Soft-Tissue Lesions. Soft tissue arises from the mesenchyme, which differentiates during development to become fat, skeletal muscle, peripheral nerves, blood vessels, and fibrous tissue ().Soft-tissue tumors are histologically classified on the basis of the soft-tissue component that comprises the lesion, but this does not imply that the tumor arises from that tissue ()

Soft tissue sarcoma - Symptoms and causes - Mayo Clini

Cyst: Pictures, Causes, Types, Treatments, and Preventio

  1. Mesenchymal tissue neoplasms are soft tissue tumors, also known as connective tissue tumors, which are relatively frequent in domestic animals and have a high incidence in some species. These tumors may be located in all organs, with a higher or lower incidence in some tissues, as it will be shown
  2. Soft tissue tumors are less common in farm animals than are tumors of the skin. Included in this group of tumors are fibroma, fibrosarcoma, myxoma, myxosarcoma, neurofibroma, lipoma, smooth muscle tumor, and rhabdomyosarcoma. Multicentric lymphoma can also involve subcutaneous tissue
  3. Soft tissue masses may also originate from within the intra-articular space and include pigmented villonodular synovitis (PVNS), primary synovial chondromatosis, and lipomatous lesions. Cystic lesions, such as Baker's cysts, meniscal cysts, and proximal tibiofibular cysts, may also be manifested as juxta-articular masses
  4. Objective- To provide an overview focusing on the current concepts in the classification and diagnosis of soft tissue tumors, incorporating immunohistochemistry. This article uses examples to discuss how to use the traditional and new immunohistochemical markers for the diagnosis of soft tissue tumors

Diagnostic Approach to Soft Tissue Tumors 22 Biopsy and Resection of Soft Tissue Tumors Reporting • Surgical pathology reports for soft tissue resections should contain tumor diagnosis, histologic grade (if applicable), and margin status (if appropriate) Additional staging information (e.g., size) can be included as a checklis Sample Dictation . SOFT TISSUE TUMORS . Benign Soft Tissue Tumors. Simple Excision Most benign soft tissue tumors are treated by simple excision in which the tumor is totally removed, however, without regard to wide margins. Superficial benign soft tissue tumors involving dermis and subcutis are accompanied by a skin elipse Soft tissue cysts represent abnormal epithelium-lined cavities, which are filled with liquid (usually glandular secretions), tissue remnants or cell products. They can arise prenatally or postnatally. In contrast to maxillary cysts, in soft tissue cysts the emphasis is on clinical symptoms. Slow-growing, generally well demarcated, painless. Malignant soft tissue tumors are known as sarcomas. These tumors form in connective tissues, such as muscles, tendons, ligaments, fat and cartilage. They are different than the more common cancers (carcinomas), which are malignant tumors that form in organs or glands (e.g., breast, prostate, colon, liver, kidney, lung, thyroid gland, etc)

Jaw tumors and cysts - Symptoms and causes - Mayo Clini

Synovial cyst: also known as a ganglion cyst, is a soft-tissue lump that may occur in any joint Branchial cleft cyst: a cyst composed of epithelial cells that arise on the lateral part of the neck due to congenital failure of obliteration of the second branchial clef A contusion (bruise) is an injury to the soft tissue often produced by a blunt force, such as a kick, fall, or blow. The result will be pain, swelling, and discoloration because of bleeding into the tissue. Treatment for contusions includes rest, ice, compression, and elevation (R.I.C.E.). More serious contusions may need to be examined by a.

Malignant Soft Tissue Tumors: Types, Symptoms & Treatment

Definition of breast-conserving surgery - NCI Dictionary

Cystic Soft Tissue Mass Excisional Biopsy Sample Repor

Soft Tissue Mass Needle Biopsy is a minimally invasive procedure. During this procedure, a biopsy of the soft tissue mass tissue is performed to evaluate soft tissue mass abnormalities, such as a soft tissue mass, a soft tissue mass cyst, and for any other abnormalities that affects soft tissue mass function Visceral soft-tissue sarcomas, which comprise 15% of all soft-tissue sarcomas, present with signs and symptoms unique to their viscus of origin. For example, gastrointestinal stromal tumors (GISTs) present with GI symptoms that are usually indistinguishable from those of the more common adenocarcinomas, such as anemia, melena, abdominal pain. Looking for soft tissue cyst? Find out information about soft tissue cyst. abnormal sac in the body, filled with a fluid or semisolid and enclosed in a membrane. Cysts can be congenital but are usually acquired, the most common... Explanation of soft tissue cyst Tumors of Fat Tissue. Lipomas: Benign tumors of fat tissue. Lipomas are the most common benign soft tissue tumor. Most are found under the skin, but they can develop anywhere in the body. Many lipomas are present for years and inactive, but those that are growing lesions are probably the most commonly resected soft tissue benign tumor

Pitfall 2: Lipoma, the Most Common Soft-Tissue Neoplasm, Cannot Be Accurately Diagnosed. Lipoma is a benign proliferation of fat cells with variable amounts of fibrous tissue that primarily arises within the subcutaneous soft tissues, muscles, and even bones of the extremities. It is the most common soft-tissue neoplasm A soft tissue sarcoma that doesn't look like any normal tissue is undifferentiated or unclassified. More than half of soft tissue sarcomas develop in the arms and legs. About one-third develop in the trunk. Few develop in the head and neck. Most soft tissue sarcomas occur in adults over age 55. But about one-fifth of these tumors occur in children Enlarge Gastrointestinal stromal tumors (GISTs) may be found anywhere in or near the gastrointestinal tract.. Less frequently, GIST may arise in the appendix, gallbladder, pancreas, retroperitoneum, and paravaginal and periprostatic tissues.[] Approximately 20% to 25% of gastric GIST and 40% to 50% of small intestinal GIST are clinically aggressive.[9,10] It has been estimated that. SOFT TISSUE • TUMORS OF ADIPOSE TISSUE • FIBROUS TUMORS AND TUMOR-LIKE LESIONS • FIBROHISTIOCYTIC TUMORS • SKELETAL MUSCLE TUMORS • SMOOTH MUSCLE TUMORS • SYNOVIAL SARCOMA 73 74. SOFT TISSUE • Any nonepithelial tissue other than bone, cartilage, CNS, hematopoietic, and lymphoid tissues. 74 75 This allows a special doctor called a pathologist to see the specific cells and characteristics of the tissue sample. Doctors can then distinguish a soft tissue sarcoma from other types of benign and cancerous tumors as well as determine the specific subtype of soft tissue sarcoma that is present

Benign Tumor Surgery — Sarcoma Specialists

Malignant soft-tissue tumors of the head and neck comprise approximately 1% of head and neck malignancies 1 and between 5% and 15% of all soft-tissue sarcomas in adults. 2-4 In children, however, approximately 35% of sarcomas involve the head and neck region, reflecting the preponderance of rhabdomyosarcoma in this age group. 5,6 Both benign and malignant tumors of the skin, soft tissues, or bone can cause a knee lump. Examples include: Fibroma (benign tumor composed of fibrous or connective tissue) Lipoma (benign tumor composed of fatty tissue) Melanoma (cancer arising in the melanocytes, or pigment-producing cells, in the skin or other parts of the body Smooth muscle tumors are here considered an essentially dichotomous group composed of benign leiomyomas and malignant leiomyosarcomas. Soft tissue smooth muscle tumors with both atypia and mitotic. Soft Tissue Sarcomas. Soft tissue sarcomas are cancerous tumors that begin in the soft tissues of the body such as muscles, fat, joints, nerves, and blood vessels. They are not common, accounting for about 1% of all cancers. It is estimated that there are approximately 30 new cases of soft tissue sarcoma per year among every one million people Soft tissue sarcomas are malignant tumors that begin in soft tissue, such as muscle, fibrous tissues, tendons, fat, nerves, joint tissues and blood vessels. These tumors are rare and can form anywhere in the body. Usually, fewer than 1,000 new soft tissue sarcomas are reported in children each year in the United States


A cyst is a sac of tissue that is filled with another substance, such as air or fluid. Tumors are solid masses of tissue. Cysts can form anywhere on the body, including on the bones and soft tissues. Most cysts are noncancerous, although there are some exceptions A list of common soft tissue sarcoma histologic types and age group associations is shown in Table 53.1. Increasingly, gene expression profiles are being used to help classify and predict the biologic behavior of soft tissue tumors (1,2,3). Standard radiologic examination consists of plain x-ray films, CT, and MRI Some types of soft tissue sarcomas may form in the arms or legs, including liposarcoma, fibrosarcoma, and synovial sarcomas, among others.When a soft tissue sarcoma is found in an arm or a leg, our doctors make every effort to perform limb-sparing surgery—removing the tumor while leaving the rest of the affected limb intact and functional Soft tissue sarcoma can occur anywhere in your body, but the most common types occur in the arms and legs, and in the abdomen. Surgical removal is the most common treatment, although radiation and chemotherapy also may be recommended — depending on the size, type, location and aggressiveness of the tumor Soft tissue sarcomas can arise almost anywhere in the body. About 50 percent occur in the extremities (the arms, legs, hands, or feet), 40 percent occur in the trunk (chest, back, hips, shoulders, and abdomen), and 10 percent occur in the head and neck. The tables on pages 5 and 6 list several types of sarcomas that occur in adults and children

*Adult soft tissue sarcoma facts written by Melissa Conrad Stöppler, MD. A sarcoma is a cancer that forms in soft tissues of the body such as muscles, fat tissue, blood vessels, tendons, and nerves. Tumors of these tissues can also be benign (non-cancerous).; There are over 50 different kinds of soft tissue sarcoma Examples of oops lesions include malignant tumors that appear benign, malignancy-mimicking benign tumors, incorrect identification of epidermal inclusion cysts, and soft tissue pseudotumors. Therefore, clinical findings, laboratory data, findings from additional imaging modalities, and demographic data of patients should be considered.

A benign,intermediate, or malignant soft tissue tumor in which the line of differentiation is uncertain. Representative examples include neoplasm with perivascular epithelioid cell differentiation, alveolar soft part sarcoma, desmoplastic small round cell tumor, epithelioid sarcoma, extraskeletal myxoid chondrosarcoma, and synovial sarcoma chymal soft tissue tumors are 100-fold more prevalent than malignant soft tissue sarcomas.1 Furthermore, less than 10% of malignant sarco-mas of bone and soft tissue arise from the foot and ankle, and benign soft tissue tumors of the foot and ankle are 100 times more prevalent than malignant soft tissue masses of the foot and ankle.3 It can there These tumors are poorly confined, soft, nodular to diffuse swellings that typically involve the subcutaneous fat and underlying muscle and connective tissue stroma. Infiltrative lipomas, which dissect along fascial planes and between skeletal muscle bundles, are considered sarcomas of intermediate malignancy Lipomas are benign soft tissue tumors composed of mature white adipocytes, histologically identical to adipose fat. Overall, lipomas are the most common soft tissue tumor in adults, with an incidence of up to 2.1 per 100 individuals. In Berquist and Kransdorf's compilation, lipomas were the fifth most common soft tissue mass in the foot and.

Examples include your muscles, tendons, fat, and blood vessels. Soft tissue sarcoma is a cancer of these soft tissues. There are many kinds, based on the type of tissue they started in. They may cause a lump or swelling in the soft tissue. Sometimes they spread and can press on nerves and organs, causing problems such as pain or trouble breathing Examples of these tumors are lipoblastoma, chondroid lipoma, perineurioma, aggressive angiomyxoma, SFT of soft tissue, mixed tumor of soft tissue, parachordoma and spindle cell LPS (Singh et al., 2004). Another important pitfall in depending on FNAC in the diagnosis of STTs is misinterpretation of the cellular material

Introduction. Soft tissue malignancies are an uncommon heterogeneous group of mesenchymal lesions. They account for 1% of adult malignant tumors 1-3 and are estimated to represent about 1% of all malignant tumors with a lifetime risk of development estimated at 0.33%. 4. Long-term local and systemic disease-free survival depends on patient age and tumor type, accurate initial staging. Soft tissue tumors are comprised of a diverse group of mesenchymal lesions that include neoplasms of muscle, connective tissue, vasculature, and the peripheral nervous system [].These tumors are rare, accounting for less than 1% of all neoplasms [] and encompass more than 50 histologic subtypes [].Although the relatively low incidence and heterogeneity of this group of tumors can make initial.

In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important. Soft tissue masses in children are common heterogeneous lesions which include inflammatory, reactive, benign and malignant tumors. Most pediatric soft tissue masses are benign. It has been estimated that after excluding small benign cutaneous and subcutaneous lesions, approximately 75% of the soft tissue masses which require imaging are benign. Tumors involving skin, soft tissue and skeletal muscle of head and neck, chest wall, abdominal wall, pelvic region, back, upper and lower extremities were included in the study. Results: Fifty-seven (5.2%) patients were recognized as having malignancies on histopathological examination. The most common involvement of malignancy was basal cell. N2 - Soft tissue type perineuriomas (STP) are uncommon tumors, oral examples being very rare. They have been described in the mandible, gingiva, lips, retrotonsillar mucosa and maxillary vestibule. Herein, we report the clinicopathologic features of five STP, two affecting the buccal mucosa and three the mandible A soft-tissue sarcoma (STS) is a malignant tumour, a type of cancer, that develops in soft tissue. A soft tissue sarcoma is often a painless mass that grows slowly over months or years. They may be superficial or deep-seated. Any such unexplained mass will need to be diagnosed by biopsy. Treatment may include, surgery, radiotherapy, chemotherapy, and targeted drug therapy

Types of Soft Tissue Sarcoma: Common, Rare and More CTC

An example of such a lesion is a giant cell tumor (Figs. 12A and 12B). These tumors are typically treated via extended curettage or marginal resection with or without adjuvant therapy, and therefore additional imaging is usually required preoperatively. MRI is generally the preferred technique for assessing osseous and soft-tissue extension Sarcomas arise in tissues referred to as connective tissue, including bone, cartilage, fat, nerves, muscles, ligaments, tendons, nerves, and more. Sarcomas are often separated into two main categories; bone sarcomas that include tumors of bone, cartilage, and bone marrow, and soft tissue sarcomas Journal of Bone and Soft Tissue Tumors: Guest Editorial:The ODYSSEY: Orthopaedic Oncology My journey thus far! - Read all about the Journey of Dr Ajay Puri [One of the Finest Orthopaedic Oncology.. Soft Tissue Tumors Prepared by Kurt Schaberg Adipocytic Lipoma Specific types: Angiolipoma—Fat + prominent branching network of vessels, often with fibrin thrombi. Usu. Tender nodule on forearm. Spindle Cell Lipoma—Fat + bland spindle cells with a variably myxoid background

Benign Soft Tissue Tumors; Symptoms & Treatmen

Soft tissue sarcoma starting in the blood vessels can be angiosarcoma, hemangioendothelioma, hemangiopericytoma, or a solitary fibrous tumor. Fibrosarcoma, dermatofibrosarcoma, low-grade fibromyxoid sarcoma, and fibromatosis are sarcomas of the connective tissue. Soft tissue sarcoma tumors can affect more than one type of body tissue Soft tissue sarcomas originate in the soft tissues of the body and are most commonly found in the arms, legs, chest or abdomen. Soft tissue tumors can occur in children and adults. Rhabdomyosarcoma is the most common type of soft tissue sarcoma in children, accounting for more than half of pediatric. A ganglion cyst is a sac filled with a jellylike fluid that originates from a tendon sheath or joint capsule. The word ganglion means knot and is used to describe the knot-like mass or lump that forms below the surface of the skin. Ganglion cysts are among the most common benign soft-tissue masses Soft tissue tumors are divided into the following four categories: Benign: These usually do not recur locally, and if they do, the recurrence is nondestructive and almost always readily curable by complete local excision.Morphologically benign lesions which are extremely rare, may give rise to distant metastases that cannot be predicted on the basis of routine, histological evaluation Ganglion cysts are the most common soft tissue tumors of the hand and wrist Ganglion is a mucin-filled hernia of synovial tissues from joint capsules or tendon sheaths due to one-way valve phenomenon. The cyst expands in size and the fluid cannot flow freely back into the synovial cavity

Cyst vs Tumor: Differences, Cancer, Diagnosis, and Treatmen

Soft tissue tumors that may recur locally but have either no or an extremely low risk of metastasis Carcinosarcoma (consider the appropriate site-specific carcinoma protocol) The removal of an entire soft tissue compartment (for example, anterior compartment of the thigh, the quadriceps) or bone, or the excision of the adjacent muscle. Update on soft tissue tumors. A, Low-grade spindle cell sarcoma with immature adipocytes and non-pleomorphic lipoblasts in the low-grade dedifferentiated component (case 1). B, Within the same tumour, high-grade spindle cell sarcoma containing lipoblasts with variable nuclear pleomorphism (case 1). C, Lipogenic low-grade myxoid liposarcoma-

Soft Tissue Masses UW Orthopaedics and Sports Medicine

Benign soft-tissue tumors usually do not recur locally, and if they do, the recurrence is nondestructive and almost always readily curable by complete local excision. Morphologically benign. 26115 Soft tissue hand/finger subcutaneous less than 1.5 cm #26111 1.5 cm or greater 26116 Soft tissue hand/finger subfascial less than 1.5 cm #26113 1.5cm or greater 23 26117 Radical resection soft tissue hand/finger less than 3 cm 26118 3 cm or greater CPT® Musculoskeletal 27047 Soft tissue pelvis/hip area subcutaneous less than 3cm3 c approach to soft-tissue masses in children. List the most com-mon pseudotumors, vascular lesions, and adipocytic tumors that may manifest as soft-tissue masses in children. Describe the clini-cal and MR imaging features that aid in making the diagno-sis of pediatric soft-tissue masses Next we include several unique case reports of soft tissue tumors, including an unusual primary alveolar soft part sarcoma by Aggrawal et al, an uncommon example of dedifferentiated solitary fibrous tumor by Roitman et al, and an inflammatory myofibroblastic tumor by Barbieri et al. Also included is a brief description of a pleomorphic. Also, make sure you look at the often overlooked soft tissue excision codes which are coded by site, size as well as depth (subcutaneous, subfascial, etc.). These are usually appropriate for deeper cysts like lipomas. For example... Site: Trunk/Back 21930 Excision, tumor, soft tissue of back or flank, subcutaneous; less than 3 c

Soft tissue cyst definition of soft tissue cyst by

Soft tissue sarcomas are a group of rare cancers affecting the tissues that connect, support and surround other body structures and organs. Tissues that can be affected by soft tissue sarcomas include fat, muscle, blood vessels, deep skin tissues, tendons and ligaments. Soft tissue sarcomas can develop in almost any part of the body, including. Soft tissue is all the tissue in the body that is not hardened by the processes of ossification or calcification such as bones and teeth. Soft tissue connects, surrounds or supports internal organs and bones, and includes muscle, tendons, ligaments, fat, fibrous tissue, lymph and blood vessels, fasciae, and synovial membranes. It is sometimes defined by what it is not - such as. The average age of all soft tissue tumors was 45 ± 18 (range 3 to 92) years, for all benign soft tissue tumors 40 ± 16 (range 8 to 86) years and for all malignant soft tissue tumors 57 ± 18 (range 3 to 92) years. There were no soft tissue metastases. A histogram illustrating the distribution of patient age is provided with Fig. 2 Both examples can be considered as soft tissue mass Level V 88307 although they have the lipoma diagnosis. The interpretation of them as Level V real soft tissue tumor excision is very much defensible. Soft Tissue Mass-Biopsy/Simple Excision. This denotation is not the best in the CPT manual Soft tissue sarcomas are tumors of connective tissues. Different soft tissue sarcomas are grouped together within this larger category because they have similar appearances on biopsy and similar clinical behavior in the patient. Subtypes include fibrosarcoma, hemangiopericytoma, liposarcoma, myxosarcoma, and undifferentiated sarcoma, among others

Cyst Treatment, Removal, Types & Symptom

Below are some examples of soft tissue injuries and ways to prove them in an auto accident case. Common Soft Tissue Injuries. Soft tissue injuries can affect any part of the body, but the following are the most common. Whiplash. A whiplash injury affects the major tissues of the neck. The injury arises if your head suddenly moves backward and. Adult soft tissue sarcoma is a disease in which malignant (cancer) cells form in the soft tissues of the body. Having certain inherited disorders can increase the risk of adult soft tissue sarcoma. A sign of adult soft tissue sarcoma is a lump or swelling in soft tissue of the body. Adult soft tissue sarcoma is diagnosed with a biopsy An emerging method is adapting x-ray to image soft tissue, so that its higher resolution can reveal tumors earlier than MRI or ultrasound. And now, researchers have taken the first image using the.

Practical Soft Tissue Pathology, 2nd ed

The most common types of soft tissue tumors are lipomatous (fatty) tumors, fibrous tumors, vascular tumors and nerve sheath tumors. Of the benign soft tissue tumors, a high majority are subcutaneous (just below the skin) and less than 5 cm in size, while the opposite is true of soft tissue sarcomas Superficial soft-tissue tumors— that is, tumors arising in the skin and subcutaneous tissues—are a common clinical entity. Since the mid 1990s, high-resolution ultrasound has been increasingly used as the first-line investigation to evaluate soft-tissue tumors [1-3].The benefits of ultrasound include its ready applicability and availability, high affinity at discriminating tissue layers. Immunohistochemistry for Analysis of Soft Tissue Tumors. Immunohistochemistry (IHC) is the use of antibody-based reagents for localization of specific epitopes in tissue sections. Over the past several decades, IHC has become a powerful tool to assist the surgical pathologist in many clinically critical settings A gastrointestinal stromal tumor (GIST) is a rare cancer. It is a type of soft tissue sarcoma that often begins in the abdomen. Before 1998, doctors classified GIST as leiomyosarcoma, gastrointestinal autonomic nerve tumor (GANT), or a combination of those two tumor types.. GISTs are often found during an endoscopy or CT scan for an unrelated condition Health Organization Classification of Tumors of Soft Tissue and Bone Leona A. Doyle, MD The 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone incorporates changes in tumor classification, as well as new genetic insights into the pathogenesis of many different tumor types that have emerged over the 11 years since.